| Dzina la kampani | ActiTide™ AH3 (Yosungunuka 1000) |
| Nambala ya CAS | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Dzina la INCI | Acetyl Hexapeptide-8; Glycerin; Butylene Glycol; Madzi; Hydroxyacetophenone; 1,2-Hexanediol |
| Kugwiritsa ntchito | Lotion, Serum, Chigoba, Chotsukira nkhope |
| Phukusi | 1kg/botolo |
| Maonekedwe | Madzi owonekera bwino okhala ndi fungo labwino |
| Kusungunuka | Madzi osungunuka |
| Ntchito | Mndandanda wa Peptide |
| Nthawi yosungira zinthu | zaka 2 |
| Malo Osungirako | Sungani chidebecho motsekedwa bwino pamalo ozizira komanso ouma pa 2 - 8°C. |
| Mlingo | 3.0-10.0% |
Kugwiritsa ntchito
Kafukufuku wokhudza njira zoyambira zotsutsana ndi makwinya adapangitsa kuti ActiTide™ AH3, hexapeptide yatsopano yomwe idapangidwa kudzera mu njira yasayansi kuyambira pakupanga mwanzeru mpaka kupanga GMP, ndi zotsatira zabwino.
ActiTide™ AH3 imapereka mphamvu yochepetsera makwinya mofanana ndi Botulinum Toxin Type A, pomwe imapewa zoopsa za jakisoni ndikupereka ndalama zambiri.
Ubwino Wokongoletsa:
ActiTide™ AH3 imachepetsa kuzama kwa makwinya komwe kumachitika chifukwa cha kupindika kwa minofu ya nkhope, zomwe zimakhudza kwambiri pamphumi ndi m'mitsempha ya m'mimba.
Njira Yogwirira Ntchito:
Kupindika kwa minofu kumachitika pamene neurotransmitter yatulutsidwa kuchokera ku synaptic vesicles. SNARE complex - gulu la mapuloteni a VAMP, Syntaxin, ndi SNAP-25 - ndi lofunikira kwambiri pakupanga vesicle docking ndi neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272:2634-2638). Complex iyi imagwira ntchito ngati mbedza ya ma cell, kugwira ma vesicles ndikuyendetsa membrane fusion.
Monga chitsanzo cha kapangidwe ka SNAP-25 N-terminus, ActiTide™ AH3 imapikisana ndi SNAP-25 kuti ilowe mu SNARE complex, zomwe zimapangitsa kuti igwirizane. Kusokonekera kwa SNARE complex kumasokoneza kutsekeka kwa vesicle ndi kutulutsidwa kwa neurotransmitter pambuyo pake, zomwe zimapangitsa kuti minofu ichepetse komanso kupewa makwinya ndi mapangidwe a mizere yaying'ono.
ActiTide™ AH3 ndi njira yotetezeka, yotsika mtengo, komanso yofewa m'malo mwa Botulinum Toxin Type A. Imalimbana ndi njira yomweyo yopangira makwinya koma imagwira ntchito mwanjira yosiyana.
