| Dzina lamalonda | ActiTide-AH3(Liquefied 1000) |
| CAS No. | 616204-22-9; 56-81-5; 107-88-0; 7732-18-5; 99-93-4; 6920-22-5 |
| Dzina la INCI | Acetyl Hexapeptide-8; Glycerin; Butylene Glycol; Madzi; Hydroxyacetophenone; 1,2-Hexanediol |
| Kugwiritsa ntchito | Mafuta odzola, seramu, chigoba, zotsukira nkhope |
| Phukusi | 1kg/botolo |
| Maonekedwe | Choyera mandala madzi ndi khalidwe fungo |
| Kusungunuka | Madzi sungunuka |
| Ntchito | Peptide mndandanda |
| Alumali moyo | zaka 2 |
| Kusungirako | Sungani chidebecho chotsekedwa mwamphamvu m'malo ozizira, owuma pa 2 - 8 ° C. |
| Mlingo | 3.0-10.0% |
Kugwiritsa ntchito
Kafukufuku wokhudzana ndi njira zolimbana ndi makwinya adapangitsa kuti atulutsidwe ActiTide-AH3, hexapeptide yopangidwa mwaluso kudzera munjira yasayansi kuchokera ku kapangidwe koyenera mpaka kupanga GMP, ndi zotsatira zabwino.
ActiTide-AH3 imapereka mphamvu yochepetsera makwinya yofanana ndi Mtundu A wa Toxin wa Botulinum, kwinaku ikupewa kuopsa kwa jakisoni komanso kupereka ndalama zochulukirapo.
Ubwino Wodzikongoletsa:
ActiTide-AH3 imachepetsa kuya kwa makwinya komwe kumachitika chifukwa cha kukangana kwa minofu ya nkhope, zomwe zimawonekera pamphumi ndi makwinya a periocular.
Kachitidwe Kachitidwe:
Kutsika kwa minofu kumachitika pamene neurotransmitter imatulutsidwa kuchokera ku ma synaptic vesicles. The SNARE complex - msonkhano wa ternary wa VAMP, Syntaxin, ndi SNAP-25 mapuloteni - ndizofunikira pa vesicle docking ndi neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Zovutazi zimakhala ngati mbedza yama cell, kugwira ma vesicles ndikuyendetsa kaphatikizidwe ka membrane.
Monga chojambula chojambula cha SNAP-25 N-terminus, ActiTide-AH3 imapikisana ndi SNAP-25 kuti iphatikizidwe mu zovuta za SNARE, ndikuwongolera msonkhano wake. Kuwonongeka kwa zovuta za SNARE kumapangitsa kuti vesicle docking iwonongeke komanso kutulutsidwa kwa ma neurotransmitter, zomwe zimapangitsa kuchepa kwa minofu ndikupewa makwinya ndi kupanga mizere yabwino.
ActiTide-AH3 ndi njira yotetezeka, yotsika mtengo, komanso yochepetsetsa kusiyana ndi Botulinum Toxin Type A. Imayang'ana njira yomweyo yopangira makwinya koma imagwira ntchito mosiyanasiyana.
