Dzina lamalonda | UniAPI-PBS |
CAS | 1405-20-5 |
Dzina lazogulitsa | Polymyxin B sulphate |
Maonekedwe | White kapena pafupifupi ufa woyera |
Kusungunuka | Madzi sungunuka |
Kugwiritsa ntchito | Mankhwala |
Kuyesa | Kuchuluka kwa polymyxin B1, B2, B3 ndi B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
Phukusi | 1kg net pa aluminiyamu iliyonse |
Alumali moyo | zaka 2 |
Kusungirako | Sungani pamalo ozizira ndi owuma, kutali ndi kuwala. 2 ~ 8 ℃ yosungirako. |
Kapangidwe ka Chemical |
Kugwiritsa ntchito
Polyxin B sulphate ndi cationic surfactant antibiotic, osakaniza a polyxin B1 ndi B2, amene angathe kusintha permeability wa selo nembanemba. Pafupifupi zopanda fungo. Zomverera ndi kuwala. Hygroscopic. Kusungunuka m'madzi, kusungunuka pang'ono mu Mowa.
Zachipatala zotsatira
Ma antibacterial sipekitiramu ake ndi ntchito zachipatala ndizofanana ndi polymyxin e. ali ndi inhibitory kapena bactericidal zotsatira pa Gram-negative mabakiteriya, monga Escherichia coli, Pseudomonas aeruginosa, paraescherichia coli, Klebsiella pneumoniae, acidophilus, pertussis ndi kamwazi. Kachipatala, amagwiritsidwa ntchito kwambiri pa matenda omwe amayamba chifukwa cha mabakiteriya okhudzidwa, matenda amkodzo omwe amayamba chifukwa cha Pseudomonas aeruginosa, diso, trachea, meningitis, sepsis, matenda oyaka, matenda a khungu ndi mucous nembanemba, etc.
pharmacological kanthu
Ili ndi antibacterial effect pa Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus, enterobacter, Salmonella, Shigella, pertussis, pasteurella ndi Vibrio. Proteus, Neisseria, Serratia, pruvidens, mabakiteriya a Gram-positive ndi obligate anaerobes sanali okhudzidwa ndi mankhwalawa. Panali kukana pakati pa mankhwalawa ndi polymyxin E, koma panalibe kukana pakati pa mankhwalawa ndi maantibayotiki ena.
Amagwiritsidwa ntchito makamaka pachilonda, thirakiti la mkodzo, diso, khutu, matenda a trachea omwe amayamba chifukwa cha Pseudomonas aeruginosa ndi Pseudomonas ena. Itha kugwiritsidwanso ntchito pa sepsis ndi peritonitis.